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<\/p>\nCholecalciferol, known more widely as vitamin D3, is a chemical compound belonging to the group of fat-soluble vitamins. It is formed in human skin under the influence of UVB solar radiation, but it can also be supplied with food or with supplements. Vitamin D3 is the biologically most important form of vitamin D, because in the body it is converted into calcitriol, that is the active hormone regulating numerous metabolic processes. Deficiencies of cholecalciferol are currently widespread, particularly in countries with little sunshine, and constitute a serious health problem.<\/p>\n
Although the diet is not able to fully cover the demand for cholecalciferol, certain products constitute a good source of it. These are above all oily sea fish, such as salmon, mackerel, sardines and herring, cod liver oil, egg yolks and liver. Products fortified with vitamin D are also available on the market, for example milk, margarines or some breakfast cereals. In spite of this, these amounts are usually not sufficient to ensure an optimal level in the blood.<\/p>\n
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The role of cholecalciferol in the body is exceptionally broad. Best known is its function in the regulation of calcium and phosphate metabolism and the mineralisation of bones, which is of importance in the prevention of rickets in children and osteoporosis in adults. Vitamin D3 supports the immune system, modulating the inflammatory response and increasing resistance to infections. It also affects the correct work of the muscles, the heart and the nervous system. More and more studies indicate that deficiencies of cholecalciferol may be linked with a higher risk of autoimmune diseases, diabetes, depression and cancers.<\/p>\n
A deficiency of cholecalciferol may lead to serious health consequences. In children it manifests itself as rickets, bone deformities and delayed growth. In adults a deficiency causes osteomalacia, musculoskeletal pain, greater susceptibility to fractures and a weakening of muscle strength. In addition, chronic fatigue, lowered mood and increased susceptibility to infections are observed. Laboratory tests make it possible to determine the concentration of 25(OH)D in the blood and to assess precisely whether supplementation is necessary.<\/p>\n
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Because of how widespread deficiencies are, supplementation with vitamin D3 is widely recommended. The doses should be adapted to age, body weight, lifestyle and the results of laboratory tests. The standard recommendations for adults amount to between 1000 and 2000 IU a day, although in the case of considerable deficiencies a doctor may recommend higher doses. It is important to take cholecalciferol together with fats, because vitamin D3 dissolves in lipids and in this way is better absorbed.<\/p>\n
Cholecalciferol is safe in the recommended doses, but an excess of it may lead to hypervitaminosis D. This manifests itself as a raised level of calcium in the blood, which results in kidney stones, damage to the kidneys and disturbances of heart rhythm. That is why supplementation should take place under the control of tests and in accordance with the guidelines. The best results are given by an individual adjustment of the dose on the basis of a measurement of the concentration of 25(OH)D.<\/p>\n
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More and more preparations with vitamin D3 are appearing on the supplement market, but they differ in bioavailability and effectiveness. The DWATRO Laboratories brand introduces solutions based on liposomal technology, which increases the absorbability of cholecalciferol. Thanks to this the supplements are more effective and make it possible to replenish deficiencies faster. The products of\u00a0DWATRO Laboratories<\/a>\u00a0often combine vitamin D3 with vitamin K2, which supports the correct use of calcium and additionally protects the cardiovascular system. Such a comprehensive approach makes supplementation more effective and safer.<\/p>\n In recent years the role of vitamin D3 in the immune system has been mentioned more and more often. Studies show that an appropriate level of cholecalciferol reduces the risk of viral and bacterial infections, eases the course of respiratory diseases and supports regenerative processes. Vitamin D3 also affects the expression of genes connected with the regulation of immunity, which makes it a key element of health prevention.<\/p>\n Cholecalciferol, that is vitamin D3, is one of the most important micronutrients determining human health. It is responsible for the mineralisation of bones and for the work of the muscles, the nervous system and the immune system. Its main source is synthesis in the skin, but at our latitude this is not sufficient for the greater part of the year, which is why supplementation becomes a necessity. Deficiencies of cholecalciferol are widespread and may lead to serious health disorders, whereas a correct level favours longevity and well-being. Innovative supplement formulas, such as those offered by DWATRO Laboratories, ensure high bioavailability and effectiveness, which makes it possible to take full advantage of the potential of vitamin D3 in the prevention and treatment of deficiencies.<\/p>\n My name is Dorota W\u0105tr\u00f3bska-\u015awietlikowska,<\/b> I am a pharmacist and a scientist holding the title of habilitated doctor of pharmaceutical sciences. I decided to combine my scientific knowledge and my experience in order to create dietary supplements of the highest quality.<\/p>\n My passion and main area of research are submicron dispersion systems, such as submicron emulsions, liposomes and lipospheres. After obtaining my doctorate, I turned my attention to the practical aspects of parenteral nutrition, combining the needs of the patient with the capabilities of the pharmacist. The most important things for me are quality, safety and efficacy , which is visible both in my scientific work and in my approach to creating supplements by\u00a0Dwatro Laboratories\u00ae.<\/a><\/p>\nCholecalciferol, immunity and disease prevention<\/h2>\n
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<\/p>\nSummary<\/h2>\n
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