Citrulline – a natural booster of energy, capacity and regeneration

What citrulline is

Citrulline is an organic chemical compound belonging to the group of non-protein amino acids, playing an important role in the metabolic transformations of the body. Its name comes from the Latin word Citrullus, meaning watermelon – the main natural source of this compound. Citrulline acts as an intermediate in the so-called urea cycle, in which the body neutralises the toxic ammonia formed during the metabolism of proteins. In sports supplementation and in medicine it is valued for its action that improves circulation, increases capacity and supports regeneration.

How citrulline works

In the body citrulline is converted into arginine – an amino acid that is the precursor of nitric oxide (NO). Nitric oxide widens the blood vessels, improving blood flow and the transport of oxygen to the muscles. Thanks to this, citrulline increases physical capacity, reduces the feeling of fatigue and speeds up regeneration after exertion. It also has a detoxifying action, supporting the removal of metabolic products such as ammonia and lactate.

The role of citrulline in the body

Citrulline performs many important physiological functions. It supports the work of the circulatory system, improving the elasticity of the vessels and blood pressure. It increases the inflow of nutrients to the muscles, which promotes their better nourishment and regeneration. It also affects the acid-base balance of the body, preventing the acidification of the muscles after intensive exertion. Thanks to its antioxidant properties it protects cells against oxidative stress and against damage caused by free radicals.

Citrulline in sport and physical activity

Citrulline has gained enormous popularity among athletes and physically active people. Studies confirm that its supplementation increases endurance, muscle strength and the effectiveness of training. It makes it easier to carry out longer training sessions and shortens the time needed for regeneration. It also acts as a so-called “muscle pump booster”, improving the blood supply and the volume of the muscles during exertion. This effect results from the increased production of nitric oxide and the better transport of nutrients.

Citrulline and the health of the circulatory system

Thanks to its properties that widen the blood vessels, citrulline supports the health of the heart and of the vessels. It lowers arterial blood pressure, improves circulation and may alleviate the symptoms of hypertension. In older people it supports the elasticity of the blood vessels, reducing the risk of cardiovascular diseases. It also supports the function of the endothelium, which is of key importance for the proper flow of blood.

Citrulline and potency and libido

Citrulline affects not only physical capacity, but also sexual functions. By increasing the production of nitric oxide it supports the widening of the blood vessels within the genital organs, which translates into an improvement of erection and a better blood supply to the tissues. For this reason citrulline is often described as a natural agent supporting libido and vitality, constituting an alternative to synthetic preparations.

Natural sources of citrulline

The largest amounts of citrulline occur in the flesh and in the rind of watermelon. In smaller amounts it can also be found in pumpkin, cucumbers and nuts. However, the amount of this amino acid in food is relatively low, which is why for therapeutic and sporting purposes supplements are most often used.

Supplementation with citrulline

Citrulline is most often available in the form of a powder or of capsules, frequently as citrulline malate, that is a combination of citrulline with malic acid, which improves its stability and absorbability. A typical supplementation dose amounts to from 3 to 8 grams per day, with the best effects being obtained when it is taken about 30–60 minutes before exertion. Regular use supports the capacity and regeneration of the body both in athletes and in people leading an active lifestyle.

Innovative DWATRO Laboratories supplements

The DWATRO Laboratories brand develops modern supplements containing citrulline in liposomal technology, which allows for a considerably higher bioavailability and a more effective action. The combination of citrulline with arginine, taurine and vitamin B6 intensifies the effect of widening the vessels and improving the blood supply. DWATRO Laboratories preparations are particularly recommended for physically active people and athletes, as well as for those who want to increase their energy, improve circulation and support the regeneration of the body. Thanks to the liposomal form, the active ingredients reach the bloodstream faster, ensuring clear effects after only a short time of use.

Safety of using citrulline

Citrulline is a natural and well tolerated compound. It does not cause side effects even with long-term use in the recommended doses. It does not affect blood pressure adversely in healthy people, and in some cases it may even regulate it favourably. Only with very high doses may slight stomach discomfort occur, which subsides after the portion is reduced.

Citrulline in regeneration and detoxification

Citrulline supports the process of removing ammonia from the body, which is of key importance for regeneration after physical exertion. Thanks to this it prevents the feeling of over-tiredness, muscle pain and a drop in capacity. In people exposed to stress or to a lack of sleep, citrulline helps to maintain metabolic balance, supports the detoxification of the liver and speeds up cellular regeneration.

Summary

Citrulline is an amino acid with a broad spectrum of action, supporting capacity, regeneration and the health of the circulatory system. It improves the flow of blood, increases the production of nitric oxide and supports the detoxification of the body. The regular use of supplements with citrulline brings benefits both to athletes and to people looking for a natural way to improve energy and well-being. The innovative DWATRO Laboratories preparations with citrulline in liposomal form ensure high bioavailability and rapid effects, supporting condition, regeneration and the general vitality of the body.

My name is Dorota Wątróbska-Świetlikowska, I am a pharmacist and a scientist holding the degree of habilitated doctor of pharmaceutical sciences. I decided to combine my scientific knowledge and my experience in order to create dietary supplements of the highest quality.

My passion and main area of research are submicron dispersion systems, such as submicron emulsions, liposomes and lipospheres. After obtaining my doctorate, I turned my attention to the practical aspects of parenteral nutrition, combining the needs of the patient with the possibilities of the pharmacist. What matters most to me is quality, safety and effectiveness, which is visible both in my scientific work and in my approach to creating Dwatro Laboratories® supplements.